These lines vary in diameter depending on their use, and are generally located underground. Oil and gas pipelines form extensive distribution networks-providing about 825 000 kilometers of lines in Canada to transport natural gas, liquefied natural gas products, crude oil, and other refined petroleum products. Outside of an energy context, pipelines transport other fluids like water. If hydrogen fuel gets extensively developed, pipelines will be needed to transport this secondary fuel. When discussing pipelines in an energy context, the fluids are usually either oil, oil products and natural gas. With apologies to the list maker, I revamped this to rank the top 10 by projected 2024 sales, instead of Evaluate’s net present value rankings.Pipelines are pipes, usually underground, that transport and distribute fluids. And Evaluate has added 6 must-watch experimental drugs to the top 10 as drugs fail or go on to a first approval. The latest annual list, which you can see here in their latest world preview, includes a roster of some of the most closely watched development programs in biopharma. VX-659/VX-445 + Tezacaftor + Ivacaftor - it’s been whittled down to 445 now - was singled out by Evaluate Pharma as the late-stage therapy most likely to win the crown for drug sales in 5 years, with a projected peak revenue forecast of $4.3 billion. But the flip side of that coin is a highly admired R&D and commercial operation that regularly wins kudos from analysts for their ability to engineer greater cash flow from the breakthrough drugs they create.īoth aspects needed for success in this business are on display in the program backing Vertex’s triple for cystic fibrosis. Vertex comes in for a substantial amount of criticism for its no-holds-barred tactical approach toward wresting the price it wants for its commercial drugs in Europe.
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